Investigating the association between neuroimaging outcomes and
neuropsychiatric symptoms in cognitively normal elderly and individuals with 


   Note: An Official Proposal has not been Submitted to NACC.


   Lead Investigator:    Myuri Ruthirakuhan
   Institution      :    Sunnybrook Research Institute
   E-Mail           :    myuri.ruthirakuhan@gmail.com
   Proposal ID      :    1675



   Proposal Description:
   Study aims: To investigate differences in the association between neuropsychiatric symptoms and:      1) structural MRI volumes in cognitively normal (CN) elderly and individuals with neurocognitive disorders (NCDs) (Mild Cognitive Impairment, Alzheimer's disease, Lewy Bodies Dementia, Frontotemporal Dementia, and Vascular Dementia).  2) cortical thinning in CN elderly and individuals with NCDs  3) white matter hyperintensity volumes in CN elderly and individuals with NCDs  4) diffusion weighted imaging (DWI) metrics in CN elderly and individuals with NCDs